Book Appointment Now
UMP·Na2 CAS：3387-36-8
We supply high purity Uridine 5′-Monophosphate Disodium Salt UMP Na2 food pharma grade with HPLC 98%-99%. Enzymatic synthesis, full COA, low MOQ 1kg, bulk drum packaging for global food additive, drug intermediate & lab research buyers.
Product Specs
Uridine 5′-Monophosphate Disodium Salt (UMP Na2) Bulk Supply
Premium Grade UMP Disodium Manufacturer & Global Supplier
High purity (HPLC ≥98.0% / ≥99.0%), non-chemical yeast RNA enzymatic hydrolysis route, with complete COA, MSDS, and global shipping support.
1. Basic Chemical Identity & Specifications
| Item | Parameter |
|---|---|
| Full Chemical Name | Uridine 5′-Monophosphate Disodium Salt |
| Common Aliases | UMP Na2, 5′-UMP Disodium, Disodium Uridylate, Uridylic Acid Disodium Salt |
| CAS Number | 3387-36-8 |
| EINECS | 222-211-9 |
| Molecular Formula | C9H11N2Na2O9P (Tetrahydrate form mainstream for industrial supply) |
| Anhydrous Molecular Weight | 368.15 |
| Hydrate Molecular Weight | ~440.20 |
| Optical Rotation | [α]D20 = -14° (c=1, purified water) |
| Melting Point | 208–210°C (Thermal decomposition) |
2. Physical & Solubility Properties
- Appearance: White crystalline powder, slight natural umami taste.
- Hygroscopy: Strong moisture absorption; must be stored in a sealed moisture-proof package.
- Solubility (20°C Water): 41g per 100mL, forms a fully clear aqueous solution.
- Insoluble: Insoluble in ethanol, acetone, and ether; slightly soluble in methanol.
- UV Characteristic Absorption: λmax = 262nm in 0.01mol/L HCl; standard absorbance ratio A250/A260: 0.70–0.78, A280/A260: 0.34–0.42.
3. Quality Standard Index (Two Industrial Grades)
4. Production Process & Quality Control System
All UMP disodium products adopt the yeast RNA enzymatic hydrolysis route, which provides higher purity and safety compared to chemical synthesis.
Step 1: Raw Yeast RNA Material Screening
▼
Step 2: Specific Nuclease Directional Cleavage
▼
Step 3: Ion Exchange Resin Monomer Separation
▼
Step 4: Sodium Neutralization Crystallization
▼
Step 5: Low-Temperature Vacuum Drying
▼
Step 6: Sterile Crushing & Sifting
▼
Step 7: HPLC Batch Inspection Before Packaging
Our QC lab is fully equipped with High-Performance Liquid Chromatographs (HPLC), UV Spectrophotometers, ICP Heavy Metal Testers, and Microbial Incubators. Every shipment provides an official COA matching the batch number.
5. Packaging, Storage & Logistics Parameters
Packaging Options
• 1kg aluminum foil vacuum bag (sample & small batch)
• 25kg fiber drum with double PE inner bags (mass wholesale)
Shelf Life & Storage
• 24 months shelf life.
• Store at 2–25°C in a cool, dry, sealed environment. Avoid direct sunlight, high humidity, and strong acids/alkalis. Seal immediately after opening.
Logistics & Delivery
• Non-dangerous chemical goods.
• In-stock orders ship within 3–7 working days.
• Stable monthly production capacity for customized large MT orders.
6. B2B Wholesale Service Support for Global Buyers
- Free Samples: 10–50g free test samples available (buyer only covers the freight cost).
- OEM & Neutral Packaging: Custom OEM labels and neutral packaging without factory logos are fully supported.
- Bulk Discounts: Long-term contract price discounts are offered for monthly bulk order clients.
- Complete Export Documentation: Full compliance documents provided, including COA, MSDS, Health Certificate, Commercial Invoice, and Packing List.
- Technical Support: Professional after-sales technical team available to guide formulation dosage & storage optimization.
FAQ
Certificate
COA, MSDS, and GMP PDF files are available for download.
Ensure quality compliance for pharmaceutical, biotechnology, and cosmetic applications.
Uridine 5′-Monophosphate Disodium Salt Industrial Applications & Wholesale Sourcing Guide for Global Manufacturers
Procurement Summary: Many overseas purchasing managers struggle with two major sourcing pain points: unstable product purity from small chemical traders and inconsistent microbial indicators that fail local food/pharma inspection standards. Professional biotech factories utilizing the enzymatic-process have become the top choice for long-term bulk buyers across Europe, North America, and Southeast Asia.
1. Core Introduction to Uridine 5′-Monophosphate Disodium Salt (CAS 3387-36-8)
If you run a food additive factory, nutraceutical formulation plant, pharmaceutical intermediate workshop, or biochemistry research lab, you must have searched for reliable bulk suppliers of Uridine 5′-Monophosphate Disodium Salt (UMP Na2). This natural nucleotide disodium salt carries the CAS registry number 3387-36-8, widely recognized as a multi-purpose raw material covering food fortification, savory flavor production, medical drug synthesis, and cell culture research.
Chemically, UMP disodium forms after uridine 5′-monophosphate neutralizes with sodium hydroxide, most commonly circulated as a tetrahydrate crystalline powder in global industrial supply chains. Unlike unstable free uridylic acid, the disodium salt features excellent water solubility and moderate pH stability between neutral and weak alkaline environments, perfectly matching formulation requirements for liquid beverages, powder premixes, and sterile cell culture mediums.
2. Key Industrial Use Cases of High Purity UMP Disodium Salt (B2B Buyer Scenarios)
2.1 Food Industry: Infant Formula Nucleotide & Compound Flavor Enhancer
The biggest mass consumption market of Uridine 5′-Monophosphate Disodium Salt is food manufacturing.
- Infant Formula Nutritional Fortifier: Human breast milk naturally contains a balanced UMP concentration. Supplementing this nucleotide in formula supports newborn intestinal barrier development and improves immune resistance, cutting infant diarrhea incidence in clinical feeding tests. Global baby food brands strictly select food-grade UMP that complies with GB 1886.82 and FDA food additive limits.
- I+G Compound Nucleotide Seasoning: UMP Na2 mixes with IMP disodium and GMP disodium to create a compound umami seasoning. The three nucleotides deliver strong taste synergy, lowering the required monosodium glutamate (MSG) dosage while enriching layered savory flavor. It is widely ordered by seasoning factories, instant noodle producers, and meat processing plants in bulk 25kg drums.
2.2 Pharmaceutical Sector: Nucleotide API Intermediate & Neuroprotective Raw Material
For pharmaceutical manufacturers, high purity ≥99% biochemistry grade UMP disodium acts as an irreplaceable synthesis precursor:
- Downstream Nucleotide Drugs: Factories rely on this raw material to produce UTP, UDP-glucose, polyadenuridylic acid, and the targeted anticancer drug Furtulon to treat viral infections, nervous system degeneration, and liver metabolic disorders.
- Dietary Supplements: In nutraceutical supplement production, formulators add UMP disodium to cognitive support capsules and gut repair oral powders. Clinical research via PubMed confirms that oral UMP supplements promote neuron metabolism, improve memory performance, and accelerate intestinal mucosal cell regeneration.
2.3 Biochemical Research & Cell Culture Laboratory Raw Material
CRO research institutions, university biology labs, and cell biotech companies purchase small-batch high-purity UMP disodium as an RNA transcription substrate and chromatographic reference standard. Its stable UV absorption peak at 262nm enables accurate nucleotide quantitative detection in biological samples without interference during cell incubation.
3. Why Enzymatic Hydrolysis UMP Disodium Outperforms Chemical Synthetic Products
| Comparison Features | Yeast RNA Enzymatic Hydrolysis (Our Route) | Traditional Chemical Full Synthesis |
|---|---|---|
| Toxic Residual Risk | Ultra-low risk. Uses natural yeast RNA & biological nucleases. No harmful chemical catalysts. | High risk. Uses heavy metal catalysts & strong acid solvents; trace residues are hard to eliminate. |
| Impurity Control | Single impurity peak <0.1%. Removes 99% of mixed heteronucleotides (CMP, AMP, GMP). | High concentration of heteronucleotides, disrupting formulation stability. |
| Physical Performance | Uniform crystalline powder via low-temp vacuum drying. Anti-caking & easy to mix. | Irregular particle size, prone to agglomeration and blocking automated production lines. |
4. Critical Quality Inspection Standards for Bulk Buyers
When sourcing wholesale UMP disodium salt overseas, professional purchasing teams must verify these four core inspection indicators to avoid quality loss:
1. HPLC Dry Base Purity
Food grade requires a minimum of 98%, while pharma biochemistry grade must reach a minimum of 99%. Always request the batch HPLC chromatogram.
Food grade requires a minimum of 98%, while pharma biochemistry grade must reach a minimum of 99%. Always request the batch HPLC chromatogram.
2. Heavy Metal Limits
Infant food additive batches strictly need Lead (Pb) <3ppm and Arsenic (As) <11ppm to pass international regulations.
Infant food additive batches strictly need Lead (Pb) <3ppm and Arsenic (As) <11ppm to pass international regulations.
3. Microbial Safety
Pathogens like Salmonella and E.coli must be completely undetectable, with the total aerobic plate count controlled under 1000cfu/g.
Pathogens like Salmonella and E.coli must be completely undetectable, with the total aerobic plate count controlled under 1000cfu/g.
4. Moisture Content
Excess water triggers hydrolysis degradation during long ocean shipping. Qualified UMP disodium maintains water content ≤25% (Food) or ≤24% (Pharma).
Excess water triggers hydrolysis degradation during long ocean shipping. Qualified UMP disodium maintains water content ≤25% (Food) or ≤24% (Pharma).
* We highly recommend buyers request free lab samples first to conduct third-party independent testing before signing long-term bulk supply contracts.
5. Sourcing Guide: Packaging, Lead Time & B2B Service Support
As a professional nucleotide factory with stable monthly UMP disodium output, we offer standardized solutions matching your transaction volume:
- Packaging Options: Small trial orders under 500kg use 1kg aluminum foil vacuum bags with a moisture-barrier inner layer. Mass bulk orders over 500kg adopt 25kg fiber drums lined with double-thick PE bags, stackable for container sea transport. Desiccants are included in all packaging.
- Lead Time: Standard lead time for in-stock UMP disodium is 3–7 working days after deposit confirmation.
- Supply Agreements: Clients with fixed monthly ton-level orders can sign annual framework agreements to lock factory-direct pricing and reserve dedicated production capacity.
- Export Documentation: Our export department prepares all required documents, including batch COA, MSDS, Food Health Certificates, and Certificates of Origin for hassle-free customs clearance.
6. Common Storage & Transportation Mistakes That Degrade UMP Disodium Quality
⚠️ Avoid This Critical Mistake:
Leaving packages half-opened in high-humidity warehouse environments is highly detrimental. Because of its strong hygroscopy, the powder absorbs ambient moisture, triggering hydrolysis to split into free uridine and inorganic phosphate, causing it to lose its formulation efficacy.
Two Actionable Storage Rules for Warehouse Teams:
- Store sealed UMP drums at temperatures between 2°C–25°C with warehouse humidity maintained under 40%.
- Once unpacked, transfer leftover powder into airtight sealed aluminum containers and finish usage within one month. During ocean shipping, avoid placing UMP containers near vessel boiler areas; long-term high heat accelerates product decomposition.
Partner with a Verified UMP Disodium Manufacturer
Get batch-specific COAs, pricing schedules, and 10g–50g free qualifying samples for your factory evaluation.
