NADPH CAS:53-57-6

NADPH Free Acid is a vital reduced coenzyme widely used in biochemistry, IVD reagents, biocatalysis and pharmaceutical research. As a direct manufacturer, we supply high-purity bulk products with stable quality and complete documentation for global B2B clients.

Key Product Highlights & Technical Benchmarks

Core Dimension Specifications & B2B Advantages
Purity & Activity Mainstream specifications reach ≥98% / 99% high purity via HPLC testing. Formulated for excellent biocompatibility and highly stable enzymatic catalytic activity.
Quality Control Subjected to rigorous internal factory quality inspections. Every single dispatch is accompanied by a complete verification package: COA (Certificate of Analysis), HPLC reports, and MSDS to ensure international import compliance.
Core Applications Perfectly optimized for complex enzymatic reactions, In Vitro Diagnostics (IVD) clinical test kits, and precision pharmaceutical intermediate synthesis for drug development.
Customization For bulk B2B commercial contracts, we provide multiple flexible packaging options (ranging from small R&D trial vials to multi-kilogram industrial drums) and can customize exclusive chemical grades based on your processing setups.
Supply Chain Direct manufacturer sourcing eliminates intermediate broker markups. We maintain stable year-round inventories, offer flexible MOQs, and arrange secure global cold-chain logistics.

Detailed Information

Basic Product Specifications

CAS Number 53-57-6
Molecular Formula C₂₁H₂₉N₇O₁₇P₂
Purity Grade 98% min / 99% min (Fully customizable specs available)
Appearance White crystalline powder
Available Grades Research grade, Biochemical grade, Pharmaceutical intermediate grade
Storage Condition Store tightly sealed at -20°C; keep strictly away from light, heat, and moisture.
Standard Packaging 1kg aluminum foil bag, 25kg fiber drum (OEM packaging fully accepted based on request)

Core Industrial & Commercial Applications

1. In Vitro Diagnostic (IVD) Reagents
Serves as a critical core raw material for G6PD detection kits, clinical biochemical assays, and enzyme activity testing systems, ensuring highly accurate and stable diagnostic test results.
2. Biocatalysis & Green Synthesis
Acts as an essential active cofactor for oxidoreductase enzymes, heavily applied across target chiral compound synthesis, fine chemical production, and natural product biosynthesis pathways.
3. Pharmaceutical R&D & Metabolism
Widely utilized by pharmaceutical discovery laboratories in CYP450 enzyme studies, active drug metabolism analysis, and cellular oxidative stress profiling experiments.
4. Academic & Laboratory Research
Functions as a standardized biochemical reagent for a broad spectrum of molecular biology, cell biology, and advanced pharmacological experiments in universities and research institutes worldwide.

Factory Supply Advantages & B2B Support

We are a highly specialized raw material manufacturer focused entirely on nucleotide coenzymes and premium biochemical substrates. All internal manufacturing processes strictly follow rigorous quality guidelines. To ensure seamless customs clearance and downstream compliance validation, every outbound shipment is accompanied by a full document trail:

Complete COA
HPLC Purity Reports
Compliant MSDS

We easily accommodate diverse procurement scales, fully supporting specialized sample testing, small R&D trial runs, and large-volume industrial bulk wholesale contracts. Backed by abundant year-round inventory and mature international cold-chain logistics lines, we guarantee stable, predictable, and efficient raw material dispatches to reagent factories, pharmaceutical enterprises, and biotechnology hubs globally.

FAQ

Q1: What is the difference between NADPH Free Acid and NADPH Sodium Salt?

NADPH Free Acid performs significantly better in weakly acidic reaction systems, offering superior solubility stability under those conditions. It is the preferred choice for high-precision biochemical assays and advanced pharmaceutical intermediate production. Conversely, the NADPH Sodium Salt form is better optimized for neutral buffer environments.

Q2: Which purity grade of NADPH Free Acid is suitable for IVD reagent production?

We strongly recommend our 99% ultra-high purity grade for In Vitro Diagnostic (IVD) manufacturing. Maintaining exceptionally low impurity thresholds eliminates background test interference, guaranteeing the strict baseline reliability and accuracy required for commercial diagnostic assay kits.

Q3: What are the correct storage rules to maintain NADPH activity?

The raw material must be kept tightly sealed and stored at -20°C under completely dark and dry conditions. Crucial Note: Avoid repeated freeze-thaw cycles after opening the primary package, as temperature fluctuations cause a rapid decline in biological coenzyme activity.

Q4: Do you provide samples for quality verification before bulk purchasing?

Yes. We provide complimentary, small-quantity validation sample sets to qualified B2B procurement teams. Corporate clients are only requested to cover the baseline international shipping fees for air express sample delivery.

Q5: What is your minimum order quantity for bulk NADPH Free Acid?

Our baseline commercial MOQ is 1 kg. To optimize your chemical logistics pipeline, we support mixed batch loading and arrange rapid dispatch workflows for regular bulk orders to precisely meet variable operational procurement demands.

Q6: Can NADPH Free Acid be used for cosmetic raw material synthesis?

This specific chemical form is primarily synthesized for advanced biochemistry, IVD kit manufacturing, and core pharmaceutical research. For cosmetic compound formulation or skincare additive needs, please reach out directly to our technical support team to review our dedicated alternative cosmetic-grade coenzymes.

Certificate

COA, MSDS, and GMP PDF files are available for download.

Ensure quality compliance for pharmaceutical, biotechnology, and cosmetic applications.

About NADPH

Complete Guide to NADPH Free Acid: Properties, Applications, and B2B Bulk Sourcing

NADPH Free Acid, also named Reduced Nicotinamide Adenine Dinucleotide Phosphate, is one of the most indispensable coenzymes in modern biochemistry and biotech industries. As the reduced form of NADP+, it undertakes electron transfer and hydrogen delivery in nearly all enzymatic reactions. For global B2B buyers including reagent manufacturers, pharmaceutical factories, biocatalysis enterprises, and research institutions, selecting qualified NADPH free acid directly determines the stability of final products and experimental data. This guide covers its core characteristics, mainstream application scenarios, grade selection standards, and practical bulk sourcing advice, helping professional purchasers make targeted decisions.

Physical and Chemical Properties of High-Quality NADPH Free Acid

Qualified industrial and lab-grade NADPH free acid appears as a fine white crystalline powder with excellent water solubility. Its biological activity is highly sensitive to temperature, light, and humidity, which is why professional manufacturers adopt low-temperature production and sealed packaging throughout the whole process. Standard high-purity products reach 98% or 99% purity, with strictly controlled heavy metal content and residual impurities, fully complying with international biochemical raw material safety standards.

Different from common chemical raw materials, NADPH free acid has strict activity requirements. High-quality products can maintain stable biological activity for 24 months under specified storage conditions. Inferior products with excessive impurities will lose activity quickly and interfere with enzymatic reactions. This is the key factor that distinguishes formal factory products from low-grade bulk goods in the international market. For downstream production, stable chemical properties and lasting activity are the basic guarantees for continuous mass production.

Primary Application Scenarios of NADPH Free Acid in B2B Industries

The application scenarios of NADPH free acid stretch across multiple specialized sectors of the modern bio-economy:

In Vitro Diagnostics (IVD)
Acts as a core reaction cofactor in clinical biochemical testing, G6PD deficiency detection, blood analysis, and various enzyme-linked assay kits. Reagent factories across Europe, North America, and Southeast Asia choose 99% high-purity material to eliminate impurity interference.
Biocatalysis & Green Chemistry
Provides continuous reducing power for oxidoreductases. Fine chemical factories utilize it to replace traditional chemical catalysts for the eco-friendly synthesis of chiral drugs, natural extracts, and high-value compounds, typically utilizing 98% standard grade to optimize costs.
Pharmaceutical R&D
Essential for simulation laboratories to study human drug-metabolism environments, interaction mechanisms with CYP450 enzymes, and cellular oxidative stress responses. Demands stable research-grade powder for repeatable experimental data.

How to Select the Right Grade of NADPH Free Acid for Your Business

B2B purchasers need to match product grades according to actual usage scenarios, which can effectively control procurement costs while meeting production demands:

  • 99% High-Purity Pharmaceutical/Biochemical Grade: The only viable option for commercial IVD reagents and pharmaceutical intermediates where strict impurity control must meet strict state health regulations.
  • 98% Standard Biochemical Grade: A highly cost-effective option engineered for industrial biocatalysis and large-batch chemical synthesis where basic activity and pricing competitive edge are balanced.
  • Research Grade: Recommended for laboratory formulation exploration, academic verification, and small-scale trial runs demanding stable batch-to-batch predictability.
Pro Procurement Tip: Before placing large bulk orders, professional buyers are advised to request active samples for pre-testing. Evaluating the solubility and reaction kinetics inside your exact manufacturing setup is the most reliable strategy to eliminate procurement risk.

Key Points for B2B Bulk Sourcing and Storage of NADPH Free Acid

When sourcing NADPH free acid internationally, verifying supplier qualifications is the first step. Reliable manufacturers will provide complete COA, HPLC test reports, MSDS, and production qualification documents. For products exported to overseas markets, confirm that the goods comply with local chemical import regulations to prevent customs clearance problems.

Operational Aspect Standard Protocol & Guidelines
Industrial Packaging 1kg moisture-proof aluminum foil bags for lab and trial use; 25kg light-proof sealed fiber drums for large scale commercial contracts.
Logistics & Shipping Specialized low-temperature and cold-chain air or sea transport deployment to actively safeguard enzymatic structural activity against thermal breakdown.
Daily Warehouse Storage Must be kept permanently sealed in a dark -20°C cold-storage facility. Alleviate Degradation: Divide materials into small working portions upon opening to avoid repeated freeze-thaw cycles.

Market Trends in the Global Biochemical Raw Material Industry

Driven by the rapid development of the global IVD industry, biopharmaceuticals, and green biocatalysis, the international demand for high-quality NADPH free acid keeps growing year by year. Downstream enterprises are actively prioritizing product stability, batch consistency, and reliable supply continuity over simple low-cost margins.

✔ Establishing long-term, factory-direct cooperation with verified coenzyme manufacturers ensures your enterprise secures optimized volume pricing tiers, consistent batch specifications, and dedicated one-stop technical support.

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