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Coenzyme Q10 CAS ：303-98-0
We are professional China manufacturer supplying food/pharma/cosmetic grade Coenzyme Q10 raw powder, including oxidized ubiquinone and reduced ubiquinol types with purity 98%-101% complying with USP, EP, BP standards. Our CoQ10 adopts microbial deep fermentation craft, stable batch quality, in stock bulk shipment, custom packaging & free COA document support for global nutraceutical, pharmacy and cosmetic brand buyers.
Coenzyme Q10 (CoQ10) Raw Powder
✅ Purity & Quality
- 99% Ubiquinone | 98% Ubiquinol
- HPLC tested purity guaranteed
✅ Production & Supply
- Microbial fermentation (no chemical impurities)
- Stable annual output: 350+ tons
✅ Applications
- Dietary supplements | Pharmaceuticals
- Skincare anti-aging | Pet nutrition
✅ Certifications
ISO22000, HALAL, KOSHER, COA, SGS third-party test reports
✅ Order & Storage
- MOQ: 1kg sample | Bulk: 25kg/drum
- Packaging: 1kg aluminum bag | 25kg fiber drum
- Cool dry storage | 36 months shelf life
Detailed Information
CoQ10 Basic Chemical Specifications
| Item | Parameter Detail |
|---|---|
| CAS No. | 303-98-0 |
| Molecular Formula | C₅₉H₉₀O₄ |
| Molecular Weight | 863.36 |
| Appearance | Ubiquinone: Orange yellow crystalline powder; Ubiquinol: Off-white crystalline powder |
| Solubility | Liposoluble, soluble in chloroform, acetone, insoluble in water |
| Test Method | HPLC |
| Purity Range | 98.0% ~ 101.0% |
Production Craft Advantages
Our high-quality CoQ10 is produced by mature microbial fermentation technology with selected high-yield Rhodotorula strains. The whole production process is finished in fully automatic fermentation tanks under GMP clean workshops.
Different from low-cost chemically synthesized CoQ10 which has hidden risks of heavy metal residues, we strictly control pH value, dissolved oxygen and temperature throughout the production process. All production batches are retained with samples for 24 months to realize full traceability, effectively reducing batch abnormal risks for downstream formulation manufacturers.
Grade Classification & Applications
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Pharmaceutical Grade CoQ10
Complies with USP/EP pharmacopoeia standards, low heavy metal and residual solvent content. Widely used as raw material for prescription auxiliary medicines for myocardial ischemia and statin adjuvant preparations.
-
Food Supplement Grade CoQ10
Meets EU food additive regulations. It is the main raw material for heart health softgels, capsules, sports nutrition powder and anti-fatigue functional beverages.
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Cosmetic Grade CoQ10
With strict microorganism control. Added into anti-aging serums, repair creams and sunscreens to deliver excellent antioxidant and anti-photoaging effects.
-
Pet Nutrition Grade CoQ10
Adopts customized stable and cost-effective formula. Served as bulk additive for cardiac care feed of dogs and cats.
Packaging & Global Logistics
Standard Export Packaging: 1kg vacuum aluminum foil bag, 25kg sealed fiber drum with inner PE bag. OEM customized packaging with private label is supported.
Global Logistics Service: We cooperate with world-class freight forwarders. Available trade terms: FOB Shanghai / FOB Guangzhou. Door-to-door DDP service is provided for bulk importers from the US, EU and Southeast Asia. Samples can be delivered within 3 working days after payment confirmation.
FAQ
Q1: What is the difference between ubiquinone CoQ10 and ubiquinol CoQ10 for bulk buying?
Answer: Ubiquinone is oxidized CoQ10, mainstream bulk raw material with competitive unit price, needs human body conversion to absorb; Ubiquinol is reduced form with 3x higher bioavailability, suitable for high-end premium supplement brands. Most mid-range brands choose ubiquinone for cost balance, luxury health product lines select ubiquinol raw powder.
Q2: Can you provide free CoQ10 sample for our lab test before bulk order?
Answer: Yes, we support 10g~100g free testing sample, buyers only bear international express freight cost; Sample attached with official COA test certificate, SGS third-party report can be provided upon request.
Q3: Is your fermentation CoQ10 compliant with EU import inspection standard?
Answer: Our CoQ10 passes EU REACH registration requirement, all batches complete heavy metal, pesticide residue and microorganism test, fully meet European customs food raw material entry standard, zero customs detention record for past 5 years of EU bulk shipments.
Q4: What is your lead time for large bulk order above 1000kg CoQ10?
Answer: Regular in-stock items ship within 5~7 working days after deposit; customized special water-soluble CWS CoQ10 needs 15~20 production days, we will confirm exact delivery schedule in proforma invoice before order confirmation.
Q5: Can CoQ10 mix with other raw materials like Ectoin for compound formulation?
Answer: CoQ10 can stably compound with Ectoin, Nicotinamide Mononucleotide and other cosmetic/health raw materials, our R&D team can provide compound formulation technical guidance for downstream factory free of charge.
Q6: How to store bulk CoQ10 raw powder to extend shelf life?
Answer: Keep sealed container in cool dry warehouse below 25℃, avoid direct sunlight and high temperature environment; Once drum opened, finish using within 3 months to prevent raw material oxidation and content reduction.
Certificate
COA, MSDS, and GMP PDF files are available for download.
Ensure quality compliance for pharmaceutical, biotechnology, and cosmetic applications.
Complete Guide to Bulk Coenzyme Q10 Raw Material for Pharma & Supplement Manufacturers
Overview: This practical sourcing guide covers specs, fermentation production, grade classification, application, and bulk purchase tips for bulk Coenzyme Q10 powder from a Chinese factory. Real industry experience helps global importers select qualified CoQ10 for supplement, pharmaceutical, and cosmetic formulation.
1. Core Chemical & Physical Properties of Industrial Bulk Coenzyme Q10
Core chemical information is the primary reference for B2B buyers to verify raw material qualification before bulk procurement. Coenzyme Q10, also known as ubiquinone with CAS: 303-98-0, molecular formula C59H90O4, and molecular weight 863.36.
- Two Main Commercial Types: Oxidized ubiquinone & reduced ubiquinol, different in appearance, absorption efficiency and application.
- Appearance: Regular ubiquinone = Orange-yellow crystalline solid; Ubiquinol = Off-white crystal.
- Solubility: Fat-soluble ingredient, soluble in acetone & chloroform, insoluble in pure water. Customized CWS Water-soluble CoQ10 for beverages & liquid supplements via microcapsule technology.
- Purity Standard: 98.0% – 101.0% (HPLC test), compliant with USP, EP and BP pharmacopoeia.
2. Fermentation Production Technology & Strict In-house QC Management
Modern qualified bulk CoQ10 adopts microbial deep fermentation as the core craft, replacing outdated animal organ extraction and full chemical synthesis, which is the standard for formal Chinese export manufacturers.
Core Production Workflow
- Strain preservation and activation
- Seed liquid expansion culture
- Large bioreactor fermentation
- Crude liquor separation & purification
- Finished recrystallization refining
Technicians dynamically adjust temperature, dissolved oxygen, and medium concentration to control impurities and batch stability. All batches keep reserve samples for over 24 months to realize full production traceability.
Full-Range Quality Control
- Full-process testing from raw materials to finished goods
- Routine tests: HPLC purity, heavy metal, residual solvent, microorganism
- Monthly third-party SGS random inspection, compliant with EU REACH & US FDA standards
Factory annual output: Over 350 tons, supporting stable large-volume global bulk supply all year round.
3. Four Core Application Fields & Recommended Dosage
Global CoQ10 bulk demand focuses on 4 mature downstream industries, with matched grades and fixed addition proportions as below:
✅ Dietary Supplement (60% Global Consumption)
Food-grade 98% ubiquinone for heart health capsules, anti-fatigue powder & nutritional tablets. Dosage: 50 mg- 300 mg per capsule. Widely compounded with nicotinamide and NMN for anti-aging products.
💊 Pharmaceutical Manufacturing
Pharmacopoeia-grade (USP/EP) CoQ10 for prescription medicines. Used for myocardial discomfort, chronic cardiac problems, and statin-induced myalgia as an adjuvant drug. Strict control on endotoxin & related substances.
🧴 Cosmetic Raw Material
Cosmetic-grade CoQ10 for anti-aging essence, sunscreen & repair cream. Addition rate: 0.1% – 1%. Combined with Ectoin for sensitive skin repair formulas.
🐾 Pet Nutrition (Fast-growing Market)
Special stable CoQ10 for pet cardiac care feed additives, popular for mid-to-high-end pet health products for dogs and cats.
4. Key Practical Buying Advice for Global Importers
Follow these tips to avoid procurement disputes when sourcing bulk CoQ10 from Chinese manufacturers:
- Confirm Grade & Standards First: Distinguish pharma/food / cosmetic / pet grade to avoid formulation loss.
- Request Free Samples: 10g – 100g free samples with official COA report (buyer only pays for international express).
- Packaging & Storage: Standard package: 1kg vacuum aluminum foil bag / 25kg PE lined fiber drum. Custom package for orders over 500kg. Store below 25℃, sealed & dry. Shelf life: 36 months.
- Lead Time & Trade Term: In-stock goods: ship within 3~7 working days after deposit. Custom microencapsulated CoQ10: 15~20 working days. Popular term: FOB Shanghai.
5. Recent Global Market Trend of Bulk CoQ10 Trade
Driven by an aging population and rising cardiovascular nutrition awareness, global CoQ10 import demand keeps steady growth across North America, Europe, and Southeast Asia.
- China is the world’s largest fermented CoQ10 production base, with mature technology and cost-performance advantages.
- One-stop compound procurement: Importers prefer to purchase CoQ10 together with Ectoin, NMN and other functional raw materials to cut costs.
- Certification advantage: Manufacturers with HALAL, KOSHER, and ISO22000 will gain a larger market share under stricter global ingredient supervision.
